101 Thromboelastography versus Conventional Coagulation Tests in Pit Viper Envenomation and Antivenom Response

Persistent pit viper envenomation in a cat

Case summary A 4-year-old female spayed, indoor/outdoor domestic mediumhair cat presented with multiple bleeding puncture wounds and hemorrhagic shock. The cat was diagnosed with suspected pit viper envenomation based on the location and appearance of the bite wounds, as well as the presence of severe coagulopathy with prolonged activated coagulation time (762 s), which responded to antivenom a...

Green pit viper antivenom from Thailand and Agkistrodon halys antivenom from China compared in treating Cryptelytrops albolabris envenomation of mice.

OBJECTIVE To compare the relative efficacy of the green pit viper antivenom from Thailand and Agkistrodon halys antivenom from China. DESIGN. In-vivo experimental study. SETTING A wildlife conservation organisation, a university, a poison information centre, and a regional hospital in Hong Kong. MAIN OUTCOME MEASURES Pre- and post-antivenom lethal dose 50 (LD50) of the Cryptelytrops albolab...

Comparison of F(ab')2 versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial

BACKGROUND Crotalidae Polyvalent Immune Fab (Ovine) has been the only antivenom commercially available in the US since 2007 for treatment of Crotalinae envenomation. Late coagulopathy can occur or recur after clearance of Fab antivenom, often after hospital discharge, lasting in some cases more than 2 weeks. There have been serious, even fatal, bleeding complications associated with recurrence ...

Pit Viper Envenomation In Dogs: Pathophysiology and Treatment

Surgical considerations in the management of pit viper snake envenomation.

Envenomation by North American pit viper snakes (family Viperidae, subfamily Crotalinae, genera Crotalus [rattlesnakes], Sistrurus [pygmy rattlesnakes], and Agkistrodon [copperhead and cottonmouth snakes]) is a dynamic and potentially serious medical condition. Each year in the United States, approximately 9,000 patients are treated for pit viper snakebite and 5 die. Pit viper venoms are comple...